Program
Please find the Preliminary Program and the Program Overview as PDF documents at the following links:
>> Preliminary Program
>> Program Overview
Tuesday, 5 June 2012
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Chair
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Rita Gerardy-Schahn
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15:30
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Rita Gerardy-Schahn
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Opening
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15:40
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Naoyuki Taniguchi
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Brain specific expression of glycosyltransferase
and its epigenetic regulation
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16:20
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Klaus Aktories
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Glycosylation by bacterial protein toxins
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17:00
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Coffee Break
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17:20
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Jose M. Estevez
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Sweet growth of plant cells. New players on the O-glycosylation pathway
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18:00
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Anne Harduin-Lepers
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Comprehensive analysis of sialyltransferase-related genes evolution in vertebrates: Molecular phylogeny and functional genomics approaches
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19:00
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Welcome Reception
(Landesmuseum, Willy-Brandt-Allee 5, Hannover)
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Wednesday, 6 June 2012
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Chair
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Mark von Itzstein
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09:00
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Monica Palcic
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Mechanisms of retaining glycosyltransferases
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09:30
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Steve Withers
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Glycosyltransferases: electrostatics, dynamics
and mechanisms through the “eyes” of NMR
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10:00
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Christelle Breton
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Galactolipid synthases : Structure/Function and
Evolution
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10:30
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Coffee Break
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Chair
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Yasuhiro Kajihara
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11:00
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Kaspar Locher
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Structure and reaction mechanism of the
bacterial oligosaccharyltransferase PglB
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11:30
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Yoshiki Yamaguchi
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Structural aspects of protein N-glycosylation
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12:00
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Gaëlle Batot
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Preliminary kinetic crystallographic study of
human blood group B synthase
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12:10
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Yasuhiro Kajihara
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Chemical synthesis of intentionally misfolded
homogeneous glycoprotein: a unique approach
for the study of glycoprotein quality control
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12:20
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Annika Hult
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Forssman expression on human red cells –
Biochemical and genetic evidence for a novel
histo-blood group system with implications for
pathogen susceptibility
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12:30
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Lunch Break
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Chair
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Ole Hindsgaul
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14:00
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Koichi Furukawa
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Involvement of complex carbohydrates in the
cancer phenotypes and therapeutic application
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14:30
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Hans Bakker
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Endoplasmic reticulum localized
glycosyltransferases
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15:00
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Philippe Delannoy
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The ganglioside GD2 induced the constitutive
activation of c-Met receptor in MDA-MB-231
breast cancer cell line expressing GD3
synthase
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15:10
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Alice Yu
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Important role of fucosyltransferase 1 and 2 in
breast cancer
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15:20
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Xing Li
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The regulatory role of UDP-GalNAc:
polypeptide N-acetylgalactosaminyltransferases
18 in protein O-Glycosylation
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15:30
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Coffee Break
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Chair
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Werner Reutter
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16:00
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Henrik Clausen
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Mining the elusive O-glycoproteome using Zinc
finger nuclease glycoengineered SimpleCells
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16:30
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Kelly Ten Hagen
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Essential roles for the UDP-GalNAc:polypeptide
N-acetylgalactosaminyltransferases during
development
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17:00
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Thierry Hennet
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Collagen glycosyltransferases
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17:30
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POSTER SESSION A
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Thursday, 7 June 2012
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Chair
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Irma van Die
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09:00
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Taroh Kinoshita
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Deficiencies of GPI mannosyltransferase 1
and 2 cause different fates of GPI anchored
proteins
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09:30
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Mike Ferguson
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The glycosyltransferases of Trypanosoma brucei
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10:00
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Pradman Qasba
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Structure-function analysis of the sugar donor
and acceptor binding sites of b1,4-Galactosyltransferase
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10:30
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Coffee Break
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Chair
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Philippe Delannoy
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11:00
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Frederic Bard
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The GalNAcTs activation pathway in cancer
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11:30
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Sakari Kellokumpu
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Functional organization of the Golgi N- and Oglycosylation
pathways
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12:00
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Ken Kitajima / Chihiro Sato
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A polysialyltransferase SNP in a schizophrenic
patient brings about the production of polysialic
acids showing impaired binding and signalling
of BDNF and FGF2
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12:30
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Lunch Break
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Chair
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Dirk Lefeber
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14:00
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Rick Cummings
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Functions of O-glycans in development and
hemostasis
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14:30
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Michael Tiemeyer
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Cellular and molecular mechanisms regulating tissue-specific glycan expression
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15:00
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Kei-ichiro Inamori
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Xylosyl- and glucuronyltransferase activities of
LARGE required for dystroglycan function
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15:15
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Dirk Lefeber
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Loss of complete and partial N-glycans in a
novel CDG subtype, restored by dietary
intervention
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15:30
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Coffee Break
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Chair
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Cheorl-Ho Kim
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16:00
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Herta Steinkellner
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Glycoengineering in plants towards human like
structures
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16:30
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Lai-Xi Wang
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Chemoenzymatic glycosylation engineering of
monoclonal antibodies
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17:00
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Atsushi Kuno
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Discovery of glycobiomarker for cancer and
development of simple assay kit for clinical
diagnosis
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17:30
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POSTER SESSION B
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Friday, 8 June 2012
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Chair
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Martina Mühlenhoff
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09:00
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Chris Whitfield
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Glycosyltransferases and chain termination
processes in the biosynthesis of bacterial Oantigen
polysaccharides
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09:30
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Christine Szymanski
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Comparison of bacterial oligosaccharyltransferases
for protein N-glycosylation
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10:00
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Miguel A. Valvano
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Aminoarabinose is essential for lipopolysaccharide export and intrinsic antimicrobial peptide resistance in Burkholderia cenocepacia
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10:30
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Coffee Break
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Chair
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Herbert Hildebrandt
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11:00
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Pamela Stanley
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Essential roles for glycosyltransferases in
development
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11:30
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Thomas Braulke
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Defects in GlcNAc-1-phosphotransferase cause
neurodegeneration and osteoporosis
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12:00
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Jianguo Gu
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Molecular mechanism for the regulation of Nactylglucosaminyltransferase
III expression and
its roles in epithelial-mesenchymal transition
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12:30
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Lunch Break
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Chair
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Rüdiger Horstkorte
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14:00
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Michael Pierce
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Expression of a specific glycosyltransferase is essential for embryonic stem cell differentiation
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14:30
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Shoko Nishihara
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Glycan function in the maintenance of ES cells
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15:00
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Salomé Pinho
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N-acetylglucosaminyltransferases III and V
regulate E-cadherin stability at the cell
membrane. Implications in the epithelial to
mesenchymal transition
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15:10
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Markus Sperandio
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ST3Gal-IV and ST3Gal-VI contribute to
leukocyte rolling during inflammation
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15:20
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Cheorl-Ho Kim
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Molecular glycobiology of pig CMP-N-
acetylneuraminic acid hydroxylase and
transcpritonal regulation for NeuGc as the
xenoantigenic determinant in pig-to-human
xenotransplantation
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15:30
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Coffee Break
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Chair
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Gerd Wagner
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16:00
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Tamao Endo
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Glycosylation and muscular dystrophy
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16:30
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John Yu
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Human embryonic stem cell differentiation: role
of glycosphingolipid structure
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17:00
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Franz-Georg Hanisch
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Peptide cis-control of O-linked LacdiNAc
formation and LacdiNAc-specific glycan
phosphorylation: post-translational control of
extracellular matrix glycoprotein function?
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17:10
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Cory Rillahan
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Global Metabolic Inhibitors of Sialyl- and
Fucosyltransferases
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17:20
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Gerd Wagner
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A Novel Class of Glycosyltransferase Inhibitors
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17:30
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POSTER SESSION C
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19:00
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Conference Dinner
(Neues Rathaus "Gartensaal", Trammplatz 2, Hannover)
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Saturday, 9 June 2012
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Chair
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Koichi Furukawa
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09:00
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Jamey Marth
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Glycosylation in the Metabolic Origins of Common Grievous Disease
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09:30
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Robert S. Haltiwanger
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Site-specific glycosylation of EGF repeats in
Notch
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10:00
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Hans Wandall
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A neurofibromatosis-like phenotype in
Drosophila caused by lack of glucosylceramide
extension
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10:10
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Pi-Wan Cheng
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Non-muscle myosin IIA transports a Golgi
glycosyltransferase to the endoplasmic
reticulum for recycling
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10:20
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Vaibhav Kapuria
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HCF-1 cleavage and glycosylation are distinct
activities of OGT dimers
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10:30
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Coffee Break
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Chair
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Roland Schauer
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11:00
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Jerry Hart
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O-GlcNAcylation's key roles in the diseases of
aging
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11:30
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Daan Van Aalten
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Phosphorylation versus O-glycosylation: yin
and yang?
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12:00
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Hisashi Narimatsu
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High Through-put identification of N-glycosylated proteins of many mouse
and human tissues, and Construction of a glycoprotein database, GlycoProtDB
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12:30
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End of Meeting
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